The 24-year-old has found it hard to nail down a spot in Ronald Koeman's side, and according to a report from Sport, the Dutch manager does not see him as part of his plans.
Barcelona signed Firpo in 2019 from Real Betis for €18 million and an additional €12 million in add-ons.
Apart from Napoli and Wolves, West Ham United are also said to be interested in him, but the side from Wolverhampton is the most keen.
Whilst Wolves have plenty of options at left-back, Fernando Marcal has struggled with injuries during his time at the club, and Rayan Ait-Nouri is only at Wolves on loan, and still needs to work in order to convince Wolves to turn the deal into a permanent one.
Firpo might be a very good option for Wolves, with Marcal heading towards the exit door and with Ait-Nouri's future still undecided.
Napoli on the other hand barely have any depth at left-back, with Faouzi Ghoulam facing constant injury problems and is possibly set for a move away from Naples, whilst Mario Rui has failed to impress in his absence.
As a result, Elseid Hysaj, who is actually a right-back, has had to fill in regularly, and whilst he has impressed there, he has had his problems with injuries in the past as well.
Firpo's time at Barcelona has not turned out as he expected, especially this season, where he has made just 17 appearances in all competitions, with just six of them being starts.
Barcelona want €20 million for him, but given the financial difficulties that they are currently in, they might be content with a fee lower than their asking price just to get some funds in.